Biography

I am a Senior Machine Learning Scientist at TikTok. I received my Ph.D. in Oct 2024 from UCLA, where I was honored as a recipient of the Amazon Fellowship and the UCLA Dissertation Year Fellowship.

Currently, I architect industry-scale Multi-modal LLMs (MLLM) and generative recommendation engines. My research focuses on bridging advanced deep learning with physical principles, including self-supervised learning, long-sequence modeling, and computational imaging.

Latest News

January 2026

"Multi-scale Conditional Generative Modeling for Microscopic Image Restoration" accepted by IEEE ICASSP 2026.

Selected Works

Nature Biomedical Engineering

Hallucination detection in virtual tissue staining and digital pathology

Introduced a monitoring framework using cycle-consistency and uncertainty quantification to identify neural network hallucinations, ensuring high-fidelity results in AI-driven pathology.

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Nature Machine Intelligence

Self-supervised learning of hologram reconstruction using physics consistency

Developed GedankenNet, a self-supervised model eliminating the need for labeled training data through physics-informed consistency and artificial data.

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Light: Science & Applications

Fourier Imager Network (FIN): Superior External Generalization

A Fourier-based framework processing spatial frequencies with learnable filters, exhibiting superior generalization and inference speed compared to standard CNNs.

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Recent Publications

Y. Zhang, L. Huang, et al. "Virtual staining of label-free tissue in imaging mass spectrometry." Science Advances (2025).
L. Huang, Y. Li, et al. "A robust framework for hallucination detection in virtual tissue staining." Nature Biomedical Engineering (2025).
Y. Zhang, L. Huang, et al. "Pixel super-resolved virtual staining using diffusion models." Nature Communications (2025).
G. Ma, C. Shen, J. Li, L. Huang et al. "Unidirectional imaging with partially coherent light." PNAS (2024).

Education

Ph.D. in ECE

UCLA | 2019 – 2024

B.Eng. in Optical Science

Zhejiang University | 2015 – 2019

Technical Stack

PyTorch/JAX MLLM/RecSys FlashAttention DeepSpeed vLLM/Triton